The Science Behind Her Sleep Reset

Built on peer-reviewed research

Every recommendation in Her Sleep Reset is grounded in published clinical and scientific literature. Below are the studies we draw from — sourced from leading institutions and indexed in PubMed, NIH, and major academic journals.

PubMed Indexed NIH / PMC Harvard Research Oxford Academic Frontiers in Neuroscience

These are real, published studies — not marketing claims. Each link opens the original paper or abstract on the publisher's website. We believe you deserve to see the evidence for yourself.

Why Women Sleep Differently

5 studies
1
Sex differences in insomnia: a meta-analysis
Zhang B, Wing YK — Sleep, 2006 · Cited by 1,643
Oxford Academic
2
Neurobiological and Hormonal Mechanisms Regulating Women's Sleep
Frontiers in Neuroscience, 2020
Frontiers in Neuroscience
3
Gender Difference in the Prevalence of Insomnia — A Meta-Analysis
Zeng LN et al. — PMC / NIH, 2020 · Cited by 348
PubMed Central · NIH
4
CBT-I and Women's Health: Sex as a Biological Variable
Nowakowski S — PMC / NIH, 2019 · Cited by 38
PubMed Central · NIH
5
Sex Difference in the Near-24-Hour Intrinsic Period of the Human Circadian Timing System
Harvard / Brigham and Women's Hospital — PNAS, 2011
PNAS · Harvard / NIH-funded

Hormones & Sleep Architecture

6 studies
6
Role of Ovarian Hormones in the Modulation of Sleep in Females Across the Adult Lifespan
PMC / NIH, 2020
PubMed Central · NIH
7
Female Reproductive Hormones Alter Sleep Architecture
Deurveilher S, Rusak B, Semba K — Sleep, 2011 · Cited by 76
PubMed Central · NIH
8
Impact of Sleep Patterns Upon Female Neuroendocrinology and HPA Axis Function
PMC / NIH, 2022
PubMed Central · NIH
9
The Impact of Sleep and Circadian Disturbance on Hormones and Metabolism
Kim TW et al. — PMC / NIH, 2015 · Cited by 555
PubMed Central · NIH
10
Effects of Sleep Fragmentation and Estradiol Decline on Cortisol Levels in Healthy Young Women
Cohn AY et al. — PMC / NIH, 2023 · Cited by 21
PubMed Central · NIH
11
Cortisol Dynamics and Sleep Quality: The Role of Sex and Oral Contraceptive Use
Morssinkhof MWL et al. — Psychoneuroendocrinology, 2025
ScienceDirect · Elsevier

Perimenopause, Menopause & Sleep

7 studies
12
Sleep and Sleep Disorders in the Menopausal Transition
PMC / NIH, 2018
PubMed Central · NIH
13
Sleep Disturbance and Perimenopause: A Narrative Review
PMC / NIH, 2025
PubMed Central · NIH
14
Menopause and Sleep Disorders
PMC / NIH, 2022
PubMed Central · NIH
15
Sleep Disturbance Associated with the Menopause
PubMed, 2024
PubMed · NIH
16
Longitudinal Study of Insomnia Symptoms Among Women During the Menopausal Transition
Ciano C et al. — PMC / NIH, 2017 · Cited by 94
PubMed Central · NIH
17
Insomnia and Menopause: A Narrative Review on Mechanisms and Treatments
Climacteric — Taylor & Francis, 2020
Climacteric · Taylor & Francis
18
Sleep Problems During the Menopausal Transition: Prevalence, Impact, and Management Challenges
Nature and Science of Sleep — Dove Press
Nature and Science of Sleep

Melatonin, Light & Circadian Rhythm

6 studies
19
Sleep, Melatonin, and the Menopausal Transition: What Are the Links?
PMC / NIH, 2017
PubMed Central · NIH
20
Lower Melatonin Secretion in Older Females: Gender Differences Independent of Age
PMC / NIH, 2014
PubMed Central · NIH
21
Sleep, Circadian Rhythms and Health
PMC / NIH, 2020
PubMed Central · NIH
22
Perfect Timing: Circadian Rhythms, Sleep, and Immunity — An NIH Workshop Summary
PMC / NIH, 2020
PubMed Central · NIH
23
The Influence of Blue Light on Sleep, Performance and Wellbeing: A Systematic Review
Silvani MI et al. — Frontiers in Physiology, 2022 · Cited by 237
Frontiers in Physiology
24
Blue Light Has a Dark Side
Harvard Health Publishing, 2024
Harvard Health Publishing

Sleep, Immunity & Cardiovascular Health

4 studies
25
Role of Sleep Deprivation in Immune-Related Disease Risk and Outcomes
Nature Communications Biology, 2021
Nature Communications Biology
26
Sleep Deprivation Increases Cardiac Risk in Women
PMC / NIH, 2005
PubMed Central · NIH
27
The Association Between Sleep Deprivation and the Risk of Cardiovascular Diseases
PMC / NIH, 2023
PubMed Central · NIH
28
Vagal Regulation, Cortisol, and Sleep Disruption in Women with Metastatic Breast Cancer
Palesh O et al. — PMC / NIH, 2008 · Cited by 116
PubMed Central · NIH

HRT, CBT-I & Evidence-Based Treatments

5 studies
29
Efficacy of Menopausal Hormone Therapy on Sleep Quality: Systematic Review and Meta-Analysis
Cintron D et al. — PMC / NIH, 2017 · Cited by 168
PubMed Central · NIH
30
Effects of Hormone Replacement Therapy on Mood and Sleep Quality in Menopausal Women
PubMed, 2024
PubMed · NIH
31
The Effectiveness of CBT on Insomnia Severity Among Menopausal Women: A Scoping Review
Ntikoudi A et al. — Life (MDPI), 2024 · Cited by 15
PubMed Central · NIH
32
Sex Differences in Insomnia: From Epidemiology and Etiology to Intervention
Suh S, Cho N, Zhang J — Current Psychiatry Reports, Springer, 2018 · Cited by 341
Springer Nature
33
Voice-Activated Cognitive Behavioral Therapy for Insomnia — Randomised Controlled Trial
JAMA Network Open, 2024
JAMA Network Open

Gut Health, Stress & Lifestyle Factors

4 studies
34
The Role of Gut Microbiome in Sleep Quality and Health
PMC / NIH, 2024
PubMed Central · NIH
35
Gut Microbiome and Metabolic Pathways Linked to Sleep Quality
Frontiers in Microbiology, 2024
Frontiers in Microbiology
36
Salivary Cortisol, Subjective Stress and Quality of Sleep Among Women Healthcare Professionals
Bani-Issa W et al. — PMC / NIH, 2020 · Cited by 73
PubMed Central · NIH
37
Light Exposure Behaviours Predict Mood, Memory and Sleep Quality
Siraji MA et al. — Scientific Reports (Nature), 2023 · Cited by 66
Scientific Reports · Nature
Research sourced from leading institutions

All 37 studies listed above are published in peer-reviewed journals and indexed in internationally recognised academic databases. Her Sleep Reset does not make medical claims — we translate science into practical, evidence-informed guidance.

Harvard Health NIH / PubMed Central Oxford Academic Frontiers in Neuroscience Nature Publishing JAMA Network Springer Nature

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